CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF
ESSENTIAL OIL FROM ROMANIAN SATUREJA MONTANA L.
ADRIANA TRIFAN1, ANA CLARA APROTOSOAIE1*, MIHAI BREBU2, OANA CIOANCĂ1, ELVIRA GILLE3, MONICA HĂNCIANU1, ANCA MIRON1
1Faculty of Pharmacy, University of Medicine and Pharmacy “Grigore T. Popa” Iasi, 16 Universitatii Street, 700115, Iasi, Romania
2Physical Chemistry of Polymers Laboratory, “Petru Poni” Institute of Macromolecular Chemistry, 41A Grigore Ghica
Voda Alley, 70048, Iasi, Romania
3National Institute of R&D for Biological Sciences/“Stejarul” Biological Research Centre, 6 Alexandru cel Bun Street,
610004, Piatra Neamț, Romania
*corresponding author: claraaprotosoaie@gmail.com
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Abstract:
The aim of the present study was to investigate the chemical composition and antioxidant activity of Satureja montana
essential oil of Romanian origin (S. montana EO). The essential oil was obtained by hydrodistillation from dried aerial parts
of cultivated plants in northeastern Romania. The chemical composition of S. montana EO was analysed by GC and GC-MS.
The main compounds were carvacrol (63.40%), para-cymene (10.97%) and γ-terpinene (3.70%). S. montana EO showed a
high reducing capacity (IC50 = 64.35 μg/mL), and was more effective as DPPH free radical scavenger (IC50 = 243.80 ± 4.93 μg/mL)
than ABTS. + inhibitor (IC50 = 560.86 ± 23.15 μg/mL). S. montana essential oil of Romanian origin belongs to the carvacrol
chemotype and represents a suitable agent for potential applicability in the protection of biological matrices from the free
radical-mediated oxidative stress, including ionizing radiation-induced oxidative damage.

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