ANTIBIOTHERAPY IN HOSPITAL – BETWEEN THE EFFICIENCY
AND QUALITY OF MEDICAL SERVICES. THE ROLE OF THE DRUG
COMMITTEE
LUCIA DAINA1*, GHEORGHE CARP1, CORINA NEAMȚU2, ALINA VENTER1, PETRU
ARMEAN3
1University of Oradea, Faculty of Medicine and Pharmacy, 10, 1 Decembrie Square, Oradea, Romania
2Clinical County Emergency Hospital Oradea, 37, Republicii Street, Oradea, Romania
3University of Medicine and Pharmacy “Carol Davila”, 6, Traian Vuia Street, Bucharest, Romania
*corresponding author: lucidaina@gmail.com
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Abstract:
This study represents an analysis regarding the role of the Drug Committee in controlling the intake of injectable antibiotics
at hospital level. Prescribing excess antibiotics (sometimes unwarranted), not implementing antibioprophylactic and
antibiotherapy protocols at the level of some hospital wards followed by increased costs represent some of the most poignant
problems faced by hospital management. The intervention of the Drug Committee after an increase of 63.7% in prescribed
antibiotics in May compared to January 2013 led to a decrease in injectable antibiotic prescriptions. Analysing the first two
semesters of 2013 comparatively, the median value of antibiotic intake/patient has been reduced by 14.9% in the second
semester compared to the first semester, while the quantitative intake of injectable antibiotics has also decreased by 5.4% in
the second semester compared to the first semester. Even though there has been a reduction in the antibiotic intake at hospital
level, there were no reported increases of nosocomial infections. Also, the second semester brought a decrease in the medium
hospitalization time by 5.93% compared to the first semester. The responsible use of antibiotherapy at hospital level can be
achieved through careful monitoring of qualitative indicators and responsibilizing doctors in regards to respecting therapeutic
protocols.

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