SPECTRAL AND PHOTOCHEMICAL PROPERTIES OF
HYPERBRANCHED NANOSTRUCTURES BASED ON GARDIQUIMOD
AND TPPS4
DANIEL BODA1#, CAROLINA NEGREI2#*, ANDREEA-LETIŢIA ARSENE2#, CONSTANTIN
CĂRUNTU3,4#, DUMITRU LUPULEASA2#, RODICA-MARIANA ION5,6#
1Dermato-oncology Excellence Research Centre “Carol Davila” University of Medicine and Pharmacy, 22-24, Gr.
Manolescu Street, Bucharest, Romania
2“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, Bucharest, Romania
3Immunology Department, "Victor Babes” National Institute of Pathology, 99-101 Splaiul Independentei Street Bucharest,
Romania
4Department of Physiology, “Carol Davila” University of Medicine and Pharmacy, 8 Blvd. Eroii Sanitari, Bucharest,
Romania
5National Institute of Research&Development for Chemistry and Petrochemistry - ICECHIM, 202 Splaiul Independentei
Street, Bucharest, Romania
6Valahia University, Targoviste, Romania, Materials Engineering Dept. 18-20 Blvd. Unirii, Targoviste, Romania
*corresponding author: carolina.negrei@outlook.com
#All authors had equal contribution to this research.
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Abstract:
This paper examines certain experimental studies on photophysical (absorption maxima, molar absorption coefficient) and
photochemical (singlet oxygen quantum yield) properties of Gardiquimod (GIQ) and its complex with 5,10,15,20-tetra-psulphonato-
phenyl-porphyrin (TPPS4), as new photosensitizer agent in photodynamic therapy (PDT). The absorption spectra
and atomic force microscopy are used, highlighting the complex between both compounds, and its nanometric size.

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