BIOLOGIC THERAPY IN RHEUMATOID
ARTHRITIS: RESULTS FROM THE ROMANIAN
REGISTRY OF RHEUMATIC DISEASES ONE
YEAR AFTER INITIATION
CĂTĂLIN CODREANU1*, CORINA MOGOȘAN1, RUXANDRA
IONESCU2, IOAN ANCUȚA3, DANIELA OPRIȘ2
1Clinic Center for Rheumatism Disease “Dr. Ion Stoia”, Bucharest,
Romania
2Hospital “Sfanta Maria” – Internal Medicine and Rheumatology,
Bucharest, Romania
3Hospital “Dr.Ion Cantacuzino” – Internal Medicine and Rheumatology,
Bucharest, Romania
*corresponding author: ccodreanu@clicknet.ro
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Abstract:

The extensive use of biologics in the treatment of rheumatoid arthritis (RA) has
called for a long-term evaluation of the efficacy and safety of this therapy. Patient registries
are currently used to provide real-life information on long-term efficacy and safety of
biologics, thus overcoming limitations imposed by methodologies of clinical studies.
Limited data are available from registries in Central and Eastern Europe.
"The Romanian Registry of Rheumatic Diseases" (RRBR) is an electronic
application that includes data of all RA patients treated with biologics in Romania. This
observational, prospective study initiated in February 2013, collected multiple variables:
demographics, RA therapies, disease activity, adverse events, in order to provide data for
RA patients in our country.

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