PAIN THERAPY ASSOCIATED WITH
ORTHODONTIC TREATMENT
RALUCA ALEXANDRA GRIGORE1, ANA-MARIA MIHAI1, DRAGOȘ
FLORIAN CIOLAN2*, VIORICA ȚĂRMURE3, ECATERINA IONESCU1
1University of Medicine and Pharmacy „Carol Davila” Bucharest,
Faculty of Dentistry, Department of Orthodontics and Dento-facial
Orthopedics 4-6, Eforie street, 50037, Bucharest, Romania.
2University of Medicine and Pharmacy „Carol Davila” Bucharest,
Faculty of Pharmacy, Department of Pharmaceutical Chemistry 6,
Traian Vuia street, 020956, Bucharest, Romania.
3University of Medicine and Pharmacy Cluj, “Iuliu Hatieganu”, Faculty
of Dentistry, Department of Orthodontics 33, Moţilor street, Cluj Romania
*corresponding author: dragos.ciolan@yahoo.com
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Abstract:

Orthodontics is based on tooth movement through bone resulting from the
application of mechanical forces. The bone remodeling takes place through an
inflammatory process associated with pain or discomfort. Many practitioners recommend to
their patients to use analgesics such as non-steroidal antiinflammatory drugs (NSAIDs) to
control the discomfort associated with the inflammatory process, unaware that studies have
shown that most of NSAIDs inhibit orthodontic tooth movement. This review tries to find
the best therapeutically approach in terms of pain relief and rate of orthodontic movement
based on today knowledge.

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