METHADONE PLASMA LEVELS IN HEROIN
ADDICT PATIENTS DURING SUBSTITUTION
THERAPY
ROBERT DANIEL VASILE1, DANIELA BACONI1*, CRISTINA
HUDIŢĂ2, MARIA BÂRCĂ1, CRISTIAN BĂLĂLĂU3, ANNE-MARIE
CIOBANU1
1University of Medicine and Pharmacy “Carol Davila”, Faculty of
Pharmacy, Traian Vuia 6, Bucharest, Romania
2“Sf. Stelian” Centre for Evaluation and Treatment of Addictions for
Young People, Cristian Pascal 25-27, Bucharest, Romania
3University of Medicine and Pharmacy “Carol Davila”, Faculty of
Medicine, Sf. Pantelimon Emergency Hospital, Sos Pantelimon 340 –
342, Bucharest, Romania
*corresponding author: daniela_baconi@yahoo.com
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Abstract:

Opiates, especially heroin, continue to be the main problem in terms of drug
abuse worldwide, as reveal the statistics for the treatment demand. In general, current
concerns in the field of diagnosis and treatment of heroin addiction are materialized both in
assessing the prevalence and patterns of problem drug use and analytical diagnosis of the
consumption, overdoses treatment and establishment the methadone substitution treatment
procedures. During the substitution treatment with methadone, it is noticed the need for
therapeutic intervention following a well-established treatment plan, correlation,
coordinating and adapting the treatment to the specific particularities of each patient...






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