SPECTRAL CHARACTERIZATION OF NEW 2-((4-
ETHYLPHENOXY)METHYL)-N-
(ARYLCARBAMOTHIOYL)BENZAMIDES
MIRON TEODOR CĂPROIU1, CARMEN LIMBAN2, ALEXANDRU
VASILE MISSIR2, DIANA CAMELIA NUŢĂ2*, LAURENȚIU
MORUȘCIAG2
1Romanian Academy, Organic Chemistry Center “Costin D. Nenitzescu”
202B Splaiul Independentei, 060023, Bucharest, Romania
2“Carol Davila” University of Medicine and Pharmacy, Faculty of
Pharmacy, Pharmaceutical Chemistry Department, 6 Traian Vuia Str.,
020956, Bucharest, Romania
* corresponding author: diananuta@yahoo.com
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Abstract:

We report here the characterization of the new synthesized thiourea derivatives
by IR, 1H-NMR, 13C-NMR and elemental analysis.
In the FTIR (Fourier transform infrared) spectrum the new compounds were
characterized by NH, C=N, C=S, C–H of the methyl and methylene groups, and alkyl- arylether
stretching vibrations.
The 1H-NMR spectrum in dmso-d6 confirmed the proposal structures showing
the presence of the NH group, ethyl group, and methylene group attached to the oxygen and
aromatic protons. The 13C-NMR spectrum has a singlet signal due to the C=S group, C16
being the most deshielded carbon.
The new compounds were synthesized in order to evaluate the influence of
fabricated nanomaterials on the biofilm development. The results could be of a great
interest for the biomedical field and open new directions for the design of film- coated
surfaces with antibiofilm properties.

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