EFFECTS OF A TOPICAL PREPARATION
CONTAINING SAMBUCI FOLIUM EXTRACT IN
EXPERIMENTAL MODEL OF THERMAL SKIN
BURNS ON RATS
GEORGE DAN MOGOŞANU1*, FLORINA CARMEN POPESCU2,
CRISTINA JANA BUSUIOC2, OLTIN TIBERIU POP2, LAURENȚIU
MOGOANTĂ2, HORIA PÂRVĂNESCU3, GABRIELA RĂU4, IOAN
LASCĂR5
1Department of Pharmacognosy and Phytotherapy
2Research Centre for Microscopic Morphology and Immunology
3Department of Plastic Surgery and Reconstructive Microsurgery
4Department of Organic Chemistry, Medicinal Chemistry
University of Medicine and Pharmacy of Craiova, 2–4 Petru Rareş
Street, 200349 Craiova, Romania
5Department of Plastic Surgery and Reconstructive Microsurgery,
“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu
Street, Sector 1, 020022 Bucharest, Romania
* corresponding author: mogosanu@umfcv.ro
Download Full Article

Abstract:

The astringent, anti-inflammatory, antiseptic and cicatrizing effect of a coldcream containing Sambuci folium soft extract was established in experimental model of thermal skin burns, in Wistar rats. Animals in the first group, treated with cold-cream containing 10% vegetal extract, had a favourable evolution, the wound healing being almost complete after 21 days. The reference group, treated with 1% silver sulfadiazine
cream, and the control group, treated with cold-cream base, showed a delay of wound healing, the epithelisation after 21 days being incomplete.

Top