NEW ACYLATED DERIVATIVES OF 2-METHYL-4-
OXO-QUINAZOLIN-3(4H)-IL-ACETOHYDROXAMIC
ACID
MIHAELA BRATU1, DIANA CAMELIA NUȚĂ1*, MIRON TEODOR
CĂPROIU2, ALEXANDRU VASILE MISSIR1, CARMEN LIMBAN1,
ILEANA CORNELIA CHIRIȚĂ1, LAURENȚIU MORUȘCIAG1
1University of Medicine and Pharmacy „Carol Davila” Bucharest,
Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
Bucharest, Romania, 6 Traian Vuia St., Bucharest, 020956, Romania
2The Organic Chemistry Center of Romanian Academy “C. D.
Neniţescu”, Splaiul Independenţei 202B, Bucharest, Romania
* corresponding author: diananuta@yahoo.com
DownloadDownload Full Article

Abstract:

In our research of bioactive molecules we synthesized some new substances with 4(3H)-quinazolinone structure that may have similar pharmacological properties to those of other compounds with similar structures. These compounds are acylated derivatives of 2- methyl-4-oxo-quinazolin-3(4H)-il-acetohydroxamic acid. Their chemical structures were
confirmed by elemental analysis, infrared (IR) and nuclear magnetic resonance (NMR) spectra.






Top