ANTICONVULSANT AND SEX ENHANCING
EFFECTS OF IPOMOEA HEDERACEA SEEDS
EXTRACT
MUHAMMAD ZIA-UL-HAQ1, MUHAMAMD RIAZ1, SHAKEEL
AHMAD2, LUCICA BARBES3*, VICTOR VELTER4, DIANA BADIU5,
STELA HALICHIDIS5
1The Patent Office, Kandawala Building,M.A. Jinnah Road Karachi,
Pakistan
2Department of Agronomy, Bahauddin Zakariya University, Multan-
60800, Pakistan
3Department of Chemistry and Chemical Engineering, Ovidius University
of Constanta, 124 Mamaia Avenue, Constanta-900527, Romania
4Scientometrics Office, UESFISCDI, Bucharest- 010362, Romania
5Clinical Infectious Diseases Hospital Constanta-900708, Romania
* corresponding author: lbarbes@univ-ovidius.r; lucica_2000@yahoo.com
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Abstract:
The crude methanolic extract of Ipomoea hederacea seeds also known as ivyleaved morning glory was evaluated in terms of anticonvulsant and sex enhancing effects on albino rats. Male albino rats were divided into five groups and were orally administered Ipomoea hederacea seeds extract of 25, 50 and 75 mg/kg body weight for the three groups, the remaining two groups were used as control and reference. The Ipomoea hederacea seeds extract showed anticonvulsant effects at higher concentrations (i.e. 50 and 75 mg/kgbw). Furthermore, the evaluation of sex enhancing effects showed increased level in mount frequencies, which represents an increased libido.
Our investigations have been proved to be promising in terms of future potential applications of extract as anticonvulsant and sex enhancer probably due to the presence of lysergic acid derivatives and clavine alkaloids which could be used in a range of phytochemicals composition and/or different pharmaceutical use.
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