BIOCHEMICAL MARKERS OF CALCIUM AND
BONE METABOLISM IN THE MONITORING OF
OSTEOPOROSIS TREATMENT
NOORA WAEL RASHEED1, CARMEN GABRIELA BARBU2*,
SUZANA FLOREA2, GABRIELA BRANCEANU2, SIMONA FICA2,
NICULINA MITREA1, CRISTINA MANUELA DRAGOI1, ALINA
CRENGUTA NICOLAE1, ANDREEA LETITIA ARSENE1
1University of Medicine and Pharmacy “Carol Davila”, Faculty of
Pharmacy, Dept. of Biochemistry, 6thTraianVuia, 020956, Bucharest,
Romania
2University of Medicine and Pharmacy “Carol Davila”, Faculty of
Medicine, Dept. of Endocrinology, Elias Hospital, 17 Mărăşti Bvd,
Bucharest, Romania
* corresponding author: carmen_gabriela_barbu@yahoo.co.uk
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Abstract:

Biochemical markers of bone turnover are extremely useful in monitoring the treatment in osteoporosis. Due to the fact that in postmenopausal osteoporosis, bone resorption is increased and biochemical markers are found to be significantly increased, a possible utility in evaluating the treatment effect emerged. It was proved that antiresorbtive
treatment is decreasing the bone resorbtion markers serum level, which is a relevant aspect for treatment monitoring.
The aim of the present study was to evaluate the predictive value of the bone turnover markers changes for bone mineral density response in women treated for postmenopausal osteoporosis, for one year with antiresorbtive therapy...

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