RISK FACTORS FOR CONTRAST-INDUCED
NEPHROPATHY AFTER CORONARY
ANGIOGRAPHY
CARMEN DENISE CĂLDĂRARU1*, DAN DOBREANU2, MARIA
DOGARU3, OVIDIU I. OLARIU4, GRIGORE DOGARU1
1Department of Nephrology, University of Medicine and Pharmacy Târgu
Mureș, Romania
2Department of Cardiology, University of Medicine and Pharmacy Târgu
Mureș, Romania
3Department of Pharmacology, University of Medicine and Pharmacy
Târgu Mureș, Romania
4Department of Radiology, University of Medicine and Pharmacy Târgu
Mureș, Romania
* corresponding author: caldararuc@yahoo.com
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Abstract:

Contrast-induced nephropathy (CIN) has become a significant source of hospital morbidity and mortality with the increasing use of iodinated contrast media in interventional procedures. The current understanding of the disease suggests a multifactorial aetiology and many important issues unresolved about the pathogenesis and the prophylactic strategies.
The purpose of this study was to determine risk factors for CIN pathogenesis after coronary angiography.
We retrospectively studied patients undergoing cardiac catheterization from a cardiology clinic from January 2009 to June 2010. All hospitalized patients who had serum creatinine measured one day before and 48 and 72 hours after the procedure were included.
Two subgroups were compared in terms of potential risk factors for contrast nephropathy: group A - patients with CIN and group B – patients without CIN...

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