OXIDATIVE STRESS IN ALZHEIMER’S DEMENTIA
ANDRADA IOVA1, OTILIA MICLE1*, LAURA VICAȘ2, LIANA MICLE1,
SORIN IOVA1, MARIANA MUREȘAN1, CORINA ANA IONIȚĂ3
1University of Oradea, Medicine and Pharmacy Faculty, Department of
Preclinical Disciplines, Oradea, Romania
2University of Oradea, Department of Pharmacy, Oradea, Romania
3University of Medicine and Pharmacy ”Carol Davila”, Department of
Clinical Laboratory and Food Safety, Faculty of Pharmacy, 6 Traian
Vuia Str., Bucharest, Romania
* corresponding author: micleotilia@yahoo.com
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Abstract:
The aim of this study was to evaluate oxidative stress on a group of patients with Alzheimer’s dementia (AD) and compare its parameters with a control group composed of mentally healthy subjects.
This research involves patients diagnosed with AD from the Clinical Hospital for Neurology and Psychiatry of Oradea and from nursing homes for the elderly, whose levels of malondialdehyde (MDA), carbonylated proteins (CP) and ceruloplasmin (CER) have been determined...
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