CHARACTERIZATION AND ANTIOXIDANT
ACTIVITY OF PHYTOSYNTHESISED SILVER
NANOPARTICLES USING CALENDULA
OFFICINALIS EXTRACT
IRINA FIERASCU1, IOANA-RALUCA BUNGHEZ1,*, RADUCLAUDIU
FIERASCU1, RODICA-MARIANA ION1, CRISTINA
ELENA DINU-PÎRVU2, DIANA NUŢĂ2
1National R&D Institute for Chemistry and Petrochemistry – ICECHIM,
202 Splaiul Independentei Street, 060021, Bucharest Romania,
2University of Medicine and Pharmacy,”Carol Davila’’, Faculty of
Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
*corresponding author: raluca_bunghez@yahoo.com
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Abstract:

The present paper describes an eco-friendly bottom-up approach to design
metallic nanoparticles with biomedical potential. The aim of the study was to characterize in terms of antioxidant activity the silver nanoparticles obtained using Calendula officinalis petals extract. First of all, a visual inspection confirmed the formation of silver nanostructures by colour changing of the sample. The bioreduction of silver ions was analyzed by modern analytical techniques (UV–VIS, FTIR (Fourier transformed IR spectroscopy), XRF (energy-dispersive X-ray fluorescence) spectroscopy and SEM (Scanning Electron Microscopy)). Antioxidant activity of the silver nanostructures was
evaluated using 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) method. The antioxidant activity of the phytosynthesised nanoparticles proved to be superior to the results of the extract.

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