RESEARCHES REGARDING OBTAINING
SELECTIVE EXTRACTS WITH
HYPOGLYCEMIANT PROPERTIES FROM
VEGETAL INDIGENOUS PRODUCTS (CICHORII
HERBA AND FRAXINI FOLIUM)
NOTE III. PHENOLIC COMPOUNDS ANALYSIS
FROM FRAXINI FOLIUM
TITINA ALINA IORDACHE, LAURIAN VLASE, VIORICA
ISTUDOR, CERASELA ELENA GÎRD
1University of Medicine and Pharmacy ,,Carol Davila“, Faculty of
Pharmacy, Department of Pharmacognosy, Phytochemistry,
Phytotherapy 6 Traian Vuia, 020956, Bucharest
2University of Medicine and Pharmacy "Iuliu Hatieganu", Faculty of
Pharmacy, Department of Pharmaceutical Technology and
Biopharmaceutics 13, Emil Isac, Cluj-Napoca, Cluj 400023
*corresponding author: vlaselaur@yahoo.com
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Abstract:

The aim of this study was to establish the polyphenolic derivatives content
(phenolcarboxylic acids, flavones and tannin) from Fraxini folium (Ash leaves) harvested at different stages of development compared to those from S.C. Phytotherapy Bucharest S.A, Romania, and to verify their presence by high performance liquid chromatography coupled with mass spectrometry and UV (HPLC/MS/UV). Leaves harvested in June had the highest content in polyphenolic derivatives. By HPLC/MS and HPLC/UV were identified luteolin, caftaric and gentisic acids not mentioned in the consulted literature.






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