EVALUATION OF THE ANTI-INFLAMMATORY
POTENTIAL OF SOME POLYHETEROCYCLIC
COMPOUNDS WITH THIAZOLE RING IN ACUTE
INFLAMMATION MODELS.
PART II. CELLULAR RESPONSE
ALINA ELENA PÂRVU2, CRISTINA MOGOŞAN1*, OLIVIU
VOŞTINARU1, CRISTINA POP1, VALENTIN ZAHARIA3
1Department of Pharmacology, Physiology and Physiopathology, Faculty
of Pharmacy, University of Medicine and Pharmacy“Iuliu Haţieganu”,
RO-400012,Cluj-Napoca, Romania
2 Department of Physiopathology, Faculty of Medicine, University of
Medicine and Pharmacy“Iuliu Haţieganu”, RO-400012,Cluj-Napoca,
Romania
3 Department of Organic Chemistry, Faculty of Pharmacy, University of
Medicine and Pharmacy“Iuliu Haţieganu”, RO-400012,Cluj-Napoca,
Romania
*corresponding author: cmogosan@umfcluj.ro
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Abstract:

The cellular anti-inflammatory effect of some polyheterocyclic compounds with thiazole ring was evaluated in an acute experimental inflammation model. The compounds had an anti-inflammatory effect as they decreased the white cells count, the percentage of neutrophils and the phagocyte index.

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