MODELING OF THE COMPOSITION OF A
SEMISOLID PROPOLIS PREPARATION, AND
EVALUATION OF ITS QUALITY
KRISTINA RAMANAUSKIENĖ, ASTA MARIJA INKĖNIENĖ1*,
DAIVA LESKAUSKAITĖ2
1 Lithuanian University of Health Sciences, Medicine Academy,
Pharmacy Faculty, Department of Pharmaceutical Technology and
Social Pharmacy. A. Mickevičiaus St. 9, LT – 44307 Kaunas, Lithuania
2 Kaunas University of Technology, Department of Food Technology.
Radvilėnų Rd. 19, LT-50254 Kaunas, Lithuania
*corresponding author: asta.inkeniene@med.kmu.lt
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Abstract:
The aim of the study was to select the optimal composition of semisolid using
natural materials, and to evaluate the quality of such preparation. Investigation of
rheological properties, evaluation of sensory characteristics, detection and identification of
phenolic acids using high-performance liquid chromatography (HPLC) were performed.
The results of the rheological investigations and the study of sensory properties were
evaluated, and the optimal composition of the ointment was selected: olive oil, beeswax,
cocoa butter, cholesterol, soft propolis extract, and substances that improved the sensory
characteristics. The base of the ointment ensures the stability of the semisolid when the
active component is soft propolis extract. The results of the quantitative study by high performance
liquid chromatography identified phenolic acids and determined their amounts
and showed that the predominant phenolic acids in the propolis ointment were ferulic acid
and coumaric acid. The modeled hydrophobic semisolid is a stable homogenous system
with positive sensory characteristics.
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