OXIDATIVE STRESS - A POSSIBLE LINK BETWEEN SYSTEMIC AND ORAL DISEASES
            
DANIELA MIRICESCU, MARIA GREABU, ALEXANDRA TOTAN, MARIA MOHORA, ANDREEA DIDILESCU, NICULINA MITREA, ANDREEA ARSENE*, TUDOR SPINU, COSMIN TOTAN, RADU RĂDULESCU
“Carol Davila” University of Medicine and Pharmacy, Bucharest
*corresponding author: andreeanitulescu@hotmail.com
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Abstract:

Oxidative stress (OS) plays a major role in the pathogenesis of a wide range of systemic and oral diseases. The aim of this review is to provide an overview of the ways in which OS may be considered a possible link between systemic and oral diseases. There is increasing evidence linking some oral diseases, e.g. periodontal disease to systemic diseases, such as cardiovascular diseases, metabolic syndrome, and diabetes. Tooth loss has been associated with a higher risk to develop several types of cancer. Malign progression of tumors has been correlated with the development of OS. This article summarizes the roles of OS emphasized in relevant studies, including our department experience, focused on the relationship between systemic and oral diseases.






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