EVALUATION OF PHENOLIC ACID
DERIVATIVES AND ESSENTIAL OIL CONTENT
IN SOME MELISSA OFFICINALIS L. VARIETIES.
ILIOARA ONIGA1*, LAURIAN VLASE2, ANCA TOIU1, DANIELA
BENEDEC1, MARCEL DUDA3
University of Medicine and Pharmacy “I. Haţieganu”, Faculty of
Pharmacy, 12 Ion Creangă Street, RO-400010 Cluj-Napoca, Romania
1Department of Pharmacognosy – Phytotherapy
2Department of Pharmaceutical Technology
3University of Agricultural Sciences and Veterinary Medicine Cluj-
Napoca, Faculty of Agriculture, Department of Phytotechnology
*corresponding author: ilioara4@yahoo.com
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Abstract:

Considering the importance of the active principles content in the vegetal
product for determining its good quality, we investigated phenolic acid derivatives and essential oil levels, in different Melissa officinalis L. varieties cultivated in Cluj, Romania.
The content of the essential oil, obtained by hydrodistillation, was between 0.03 – 0.10mL/100g fresh vegetal product. The phenolic acid derivatives concentrations were determined spectrophotometrically between 7.66 – 11.65 mg% (expressed in caffeic acid).
We identified caftaric and caffeic acid in all samples by HPLC analysis and p-coumaric and ferulic acid only in the hydrolyzed samples.




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