A TURBIDIMETRIC METHOD FOR
THE ASSAY OF MELOXICAM USING
MOLYBDOPHOSPHORIC ACID.
ANDREEA ELENA MURARAŞU*, MARIANA MÂNDRESCU,
ADRIAN FLORIN ŞPAC, VASILE DORNEANU
University of Medicine and Pharmacy “Gr. T. Popa” Iaşi,
Faculty of Pharmacy, Analytical Chemistry Department
University Street, no. 16, Iaşi, postal code: 700115
*corresponding author: andreea_murarasu@yahoo.com
DownloadDownload Full Article

Abstract:

A turbidimetric method was developed for the assay of meloxicam using molybdophosphoric acid in hydrochloric acid medium. The reaction product showed an absorbance maximum at 342 nm. The optimum reaction conditions were established. The developed method was validated. The method showed a good linearity in the range of 1.0 - 2.6 μg/mL (the correlation coefficient r = 0.9995). The detection limit (LD) was 0.29 μg/mL and the quantification limit (LQ) was 0.95 μg/mL. There were determined the precision (RSD = 1.79%) and the accuracy (mean recovery was 100.89% in the 98.45 - 103.22% range).




Top