LC /MS ANALYSIS OF AUCUBIN AND
CATALPOL OF SOME VERONICA SPECIES.
GIANINA CRIŞAN1*, LAURIAN VLASE2, GEORGETA BALICA1,
DANA MUNTEAN2, CRISTINA ŞTEFĂNESCU1, RAMONA
PĂLTINEAN1, MIRCEA TĂMAŞ1, SORIN LEUCUŢA2
1Department of Pharmaceutical Botany, University of Medicine and
Pharmacy “Iuliu Haţieganu”, Faculty of Pharmacy, 8, V. Babeş Street,
400012, Cluj-Napoca, Romania
2Department of Pharmaceutical Technology and Biopharmaceutics,
University of Medicine and Pharmacy “Iuliu Haţieganu”, Faculty of
Pharmacy, 8, V. Babeş Street, 400012, Cluj-Napoca, Romania
*corresponding author: gcrisan@umfcluj.ro
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Abstract:
A comparative study was performed on 12 species of the genus Veronica L.
(Plantaginaceae sensu APG 2003, formerly Scrophulariaceae) namely Veronica persica, V. bachofenii, V. urticifolia, V. agrestis, V. austriaca, V. chamaedrys, V. officinalis, V. orchidea, V. spicata, V. beccabunga, V. hederifolia, V. prostrata. In these species we have determined the aucubin and catalpol content by using a HPLC analysis with mass spectrometry detection. The content of aucubin is varying from 799.8 μg% in Veronica persica to 43.4 μg% in Veronica beccabunga. The highest content of catalpol is found in Veronica spicata (318.8 μg%) and the lowest in Veronica beccabunga (27.6 μg%), respectively.
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