ELASTIC VESICLES AS DRUGS CARRIERS THROUGH THE SKIN.
CRISTINA DINU PIRVU¹, CRISTINA HLEVCA², ALINA ORTAN³,
RĂZVAN PRISADA¹
1 ‘Carol Davila’ University of Medicine and Pharmacy, Faculty of
Pharmacy, Department of Physical Chemistry, Colloids and
Biopharmacy, Bucharest
2 National Institute of Chemical Pharmaceutical Research and
Development, Bucharest
3 University of Agricultural Sciences and Veterinary Medicine, Faculty of
Biotechnology, Bucharest
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Abstract:

Transdermal administration of drugs is generally limited by the barrier function of the skin. Vesicular systems are one of the most controversial methods for transdermal delivery of active substances. The interest in designing transdermal delivery systems was relaunched after the discovery of elastic vesicles: transferosomes and ethosomes. This paper presents the composition, manufacturing and characterization methods, mechanisms of penetration of transferosomes and ethosomes as transdermal delivery systems of active substances.

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