NEW 6,11-DIHYDRODIBENZO[b,e]THIEPINE DERIVATIVES. NOTE VI.
CAMELIA ELENA STECOZA1*, MIRON TEODOR CĂPROIU2,
CONSTANTIN DRĂGHICI2, CORINA ILIE3
1University of Medicine and Pharmacy „Carol Davila”, Faculty of
Farmacy, Pharmaceutical Chemistry Department, Traian Vuia 6, sect. 2,
020956, Bucharest, Romania
2Center of Organic Chemistry „C.D. Nenitescu”, Romanian Academy,
202 B Splaiul Independenţei, 060023, Bucharest, Romania
3National Institute for Chemical Pharmaceutical R&D – ICCF, Vitan
Avenue 112; Bucharest, Romania
*corresponding author: stecoza@yahoo.com


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Abstract:

The present paper describes the synthesis and characterization of some new 6,11- dihydrodibenzo[b,e]thiepine derivatives. The synthesis was performed in several stages via 11-hydroximino-6,11-dihydrodibenzo[b,e]thiepine, 11-hydroximino-2-methyl-6,11-dihydrodibenzo [b,e]thiepine, respectively.

The structures of the newly synthesized compounds were confirmed by elemental analysis and spectroscopic (IR, 1H NMR, 13C-NMR) data.




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