REGENERATIVE PROPERTIES OF
ALOE VERA JUICE ON HUMAN
KERATINOCYTE CELL CULTURE.
ANDRA TUDOSE1,2, CHRISTIAN CELIA1, FRANCESCO
CARDAMONE1, MARGHERITA VONO1,3, ROBERTO MOLINARO1,3,
DONATELLA PAOLINO3,*
1Department of Pharmacobiological Sciences, Faculty of Pharmacy,
University “Magna Græcia” of Catanzaro, Campus Universitario “S.
Venuta” - Building of BioSciences, Viale S. Venuta, I-88100 Germaneto
(CZ), Italy
2Department of Applied Mathematics and Biostatistics, Faculty of
Pharmacy, University of Medicine and Pharmacy “Carol Davila “
Bucharest, Romania
3Department of Experimental and Clinical Medicine, Faculty of
Medicine, University “Magna Græcia” of Catanzaro, Campus
Universitario “S. Venuta” - Building of BioSciences, Viale S. Venuta, I-
88100 Germaneto (CZ), Italy
*corresponding author: paolino@unicz.it
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Abstract:
Aloe Vera, a medicinal plant widely used in food supplements, beverages,
pharmaceuticals and cosmetics, was used as an effective natural remedy for its healing properties
and positive influence in different inflammatory skin disorders. In particular, regenerative
properties of Aloe Vera juice are investigated on human keratinocyte cells that are used as an in
vitro skin model system. The therapeutic efficacy of the plant extract was evaluated using trypan
blue assay and the counting cell determination. The obtained results showed that Aloe Vera juice
could represent a natural therapeutic strategy through the topical route.
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