CONTRIBUTIONS TO THE
PHARMACOGNOSTICAL AND
PHYTOBIOLOGICAL STUDY ON LEONURUS
CARDIACA L. (LAMIACEAE).
MARIA-LIDIA POPESCU*, MIHAELA DINU, OLIMPIA TOTH
University of Medicine and Pharmacy „Carol Davila“, Faculty of
Pharmacy, 6 Traian Vuia street, Bucharest, Romania
*corresponding author: lidiapopescu24@yahoo.com
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Abstract:

The paper presents our experimental results regarding a comparative pharmacognostical and phytobiological study of Leonurus cardiaca L., motherwort (Lamiaceae), the vegetal drugs herba-, folium-, flos-, and caulis-type. Microscopically we identified the following specific anatomical elements: unicellular trichomes, with warty cuticle and pluricellular trichomes, with smooth cuticle for Leonuri folium; unicellular trichomes, with thin and smooth cuticle for Leonuri flos respectively. The chemical analysis showed the presence of flavonoids (2.04-2.21x10^-3 g% in herb, 5.82- 6.74x10^-3 g% in leaves, 1.14-1.63x10^-3 g% in flowers, and 0.83-1.02x10^-3 g% in stems; expressed as rutin), polyphenolcarboxilic acids (62.34-65.12x10^-3 g% in herb, 89.91- 93.43x10^-3 g% in leaves, 36.47-40.18x10^-3 g% in flowers, and 12.41-15.64x10^-3 in stems; expressed as caffeic acid), iridoides, triterpenes, tannins, sterols, carotenoids, monosaccharides, and polysaccharides. Triticum bioassay revealed the up and down (two ways) effect of the tested solutions. The aqueous extracts 5.00-1.66% had concentration-dependent mitoinhibitory effect and the diluted solutions (0.33%) had a stimulating effect on radicular elongation of Triticum vulgare.

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