THE HISTOPATHOLOGICAL EXAMINATION OF
MICE TISSUES AFTER THE TREATMENT WITH
NEW SYNTHESIZED PROSTAMIDES WITH
ANTIGLAUCOMA ACTION.
DENISA IOANA UDEANU¹, MANUELA ENACHE²,
DENISA MIHELE¹, FLOREA COCU³
1University of Medicine and Pharmacy “Carol Davila”, Bucharest,
Faculty of Pharmacy, Department of Clinical Laboratory and Food
Safety, Traian Vuia 6, Sect.1, Bucharest, 020956
2Sanitary Veterinary and for Food Safety Direction, Calea Feldioarei 20A, Brasov
3National Institute for Chemical and Pharmaceutical Research and
Development, Bucharest, Calea Vitan 112, Sect.3, Bucharest
*corresponding author: denisaudeanu@gmail.com
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Abstract:

Prostamides are nowadays considered as the most effective drugs used for the long term treatment of primary open angle glaucoma. New prostamides with potential antiglaucoma action were synthesized within the Department of Biosynthesis of Natural Products from the National Institute for Chemical and Pharmaceutical Research and Development, Bucharest. The current research is part of the preliminary toxicological studies and tries to assess the possible histopathological modifications of mice tissues after the treatment with new synthesized prostamides..

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