ANALYSIS OF VOLATILE COMPOUNDS FROM
INFUSION AND HYDRODISTILLATE OBTAINED
FROM THE SPECIES THYMUS PULEGIOIDES L.
(LAMIACEAE).
VALERIA RĂDULESCU, MARIANA PAVEL, ANA TEODOR,
ALEXANDRA TĂNASE, DIANA CAROLINA ILIEŞ
University of Medicine and Pharmacy “Carol Davila” Bucharest,
Faculty of Pharmacy, 6th Traian Vuia str, Bucharest 2, 020956
*corresponding author: valeria_radulescu@yahoo.com
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Abstract:

The volatile compounds present in the species belonging to the Thymus genus (Lamiaceae) are responsible for the two well defined therapeutic effects demonstrated for these plants: antiseptic and spasmolytic effects. The essential oil which contains the majority of these compounds is hardly accessible and, as consequence, it is rarely used by the patient. That’s why an analysis of the volatile compounds in other pharmaceutical forms, such as infusion, the most often used one, and hydrodistillate obtained by a simple and fast method - open circuit distillation - was necessary.
After the extraction on solid phase (C₁₈ cartridge) of the volatile compounds from infusion and hydrodistillate their identification was performed using GC-MS. The main compounds identified in infusion were: carvacrol (38.96 %), thymol (25.17 %), linalool (9.75 %) and thymoquinone (7.27 %), and in hydrodistillate: carvacrol (63.20 %), linalool (16.95 %) and thymol (15.55 %)..

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