EXPERIMENTAL RESEARCH REGARDING THE ACTIVE EXTRACTS, POLYPHENOLS-STANDARDIZED. NOTE I. HYPERICI HERBA – PHARMACOGNOSTIC ANALYSIS OF THE RAW MATERIAL.
CERASELA ELENA GÎRD*, LIGIA ELENA DUŢU, MARIA LIDIA POPESCU, MARIANA PAVEL, ALINA TITINA STERIE
University of Medicine and Pharmacy ,,Carol Davila“, Faculty of Pharmacy, Department of Pharmacognosy Phytochemistry Phytotherapy
Traian Vuia no. 6, Bucharest, Romania
*corresponding author: cerasela.gird@yahoo.com
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Abstract:

Flowering tops of St. John’s wort (Hypericum perforatum L.) were studied, in order to obtain a selective extract, enriched in hypericin. Macroscopic exam, microscopic exam and a chemical exam (qualitative and quantitative) were performed for this raw vegetal material.
The following anatomic characteristics were identified: secretory glands with essential oil, secretory glands with hypericin; cluster-crystals of calcium oxalate; epidermis with necklace-shaped walls.
The raw material contains: flavones (1.024 – 1.043 g%, expressed as rutin), polyphenolcarboxilic acids (19.79 – 21.83 g%, expressed as caffeic acid), hypericins (0.408 – 0.428 g%, expressed as hypericin), carotenoids, tannin and polysaccharides (mucilages).
Also, a dry extract enriched in hypericins and a pharmaceutical product containing a powder of this vegetal drug were analysed by comparison to the raw material.

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