TRICHLORFON PERMEATION: A COMPARATIVE STUDY WITH DIFFERENT MEMBRANES AND ADSORPTIVE POWDERS.
MIHAELA IONESCU, CRISTINA MARIA RANETTI, ELENA IONICA, LAVINIA GEORGETA HINESCU, C. MIRCIOIU, DALIA MIRON, C. DRAGHICI, LACRAMIOARA POPA, V.A.VOICU
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Abstract:

The in vitro release of trichlorphon (TCP) from acidic solutions was studied using a static diffusion cell battery, through cellulose membranes. The amount of toxic released compound decreases in the following order: cellophane (83%), cuprophan (78%) and cellulose acetate (74%). There was also studied the influence of adsorptive powders upon the decreasing amount of the released compound. We observed that the powder mixture cellulose acetate: bentonite reduced with 45% the TCP released amount and the magnesium trisilicate: bentonite mixture, with only 11%. The release kinetics were determined using the first order model, according to the equation: w = 100 (1-e^-kt).

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