RESEARCH OF THE ACTION OF THE METHYLIC ESTERS OF THE FATTY ACIDS FROM THE EXTRA-VIRGIN OLIVE OIL ON THE BIOCHEMICAL PARAMETERS ON RAT.
DĂRMĂNESCU DIANA, DENISA MIHELE, ELENA MOROŞAN, ANCA POP , F. COCU
Download Full Article

Abstract:

The mono- and polyunsaturated fatty acids are essential for the body, being involved in diverse metabolic processes. They can be found especially in the vegetal oils and fish oil in variable proportions. In the present study we took into study the extra-virgin olive oil. We developed a transesterification method with methanol, of the extra-virgin olive oil, and obtained the correspoding methylic esthers. On these we made preliminary pharmaco-toxicological studies and we determined the influence on some biochemical parameters, glicemy, total plasmatic lipids, cholesterolemy, non proteic nitrogen compounds and the activity of the plasmatic transaminases compared with the extra-virgin olive oil. The olive oil has no toxicity and the methylic esters of the fatty acids have a low toxicity. The lipemy decreases after the treament with the methylic esters of the fatty acids with 12.24% and for the extra-virgin olive oil with 14.90%. The cholesterolemy decreases with 12.89% for the methylic esters and with 11.46% for the olive oil. The plasmatic triglycerides decrease with 14.5% for the methylic esthers and with 11.6% for the olive oil. The non-proteic nitrogen compounds, urea, creatinine, uric acid, have moderate decreases under the influence of the methylic esters of the fatty acids and of the olive oil.

Top