CONTRIBUTIONS TO THE PHARMACOGNOSTICAL AND PHYTOBIOLOGICAL STUDY OF THE LEAVES OF CIRSIUM ERISITHALES (Jacq.) Scop. (ASTERACEAE).
MARIA - LIDIA POPESCU1, MIHAELA DINU2, MIHAELA - ZENAIDA RISTACHE1
University of Medicine and Pharmacy ,,Carol Davila“, Faculty of Pharmacy, 6 Traian Vuia Street, Bucharest
1Pharmacognosy. Phytochemistry. Phytotherapy Department
2Pharmaceutical Botany Department

Abstract:

The leaves collected from Cirsium erisithales (Jacq.) Scop. (Asteraceae) were studied in order to be used in phytotherapy. This study determined the morpho-anatomical characteristics, identified the active principles and established the action on plant cell division.
Microscopically we identified the specific anatomical elements: multicellular trichomes, anomocytic stomates and cluster-crystals of calcium oxalate.
The chemical qualitative analysis showed the presence of flavones (rutin, quercetin), polyphenolcarboxilic acids (caffeic acid, chlorogenic acid), sterols, triterpenes, tannins, carotenoids, coumarins, nitrate compounds, mono and polysaccharides.
This vegetal product contains: 0.45 – 0.53 g% flavones (expressed as rutin) and 0.19 – 0.23 g% polyphenolcarboxilic acids (expressed as caffeic acid).
The phytobiological researches established a total mitoinhibitory action for the aqueous extract 5 %. The extract was not citotoxic.

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