NEW SOURCES OF ACTIVE PRINCIPLES
NOTE 1. CONTRIBUTIONS TO THE PHARMACOGNOSTIC AND PHYTOBIOLOGIC STUDY OF THE SPECIES CLEMATIS VITALBA L..
CERASELA ELENA GÎRD1, MARIANA PAVEL1, MARIANA PANŢUROIU2, MIHAELA DINU3, ALINA MARIA PETRE1, I. CIULEI

1University of Medicine and Pharmacy ,,Carol Davila“, Faculty of Pharmacy, Traian Vuia no.6, Bucharest, Departement of Pharmacognosy, Phytochemistry, Phytoterapy
2Fildas Trading, Bucharest
3University of Medicine and Pharmacy ,,Carol Davila“, Faculty of Pharmacy, Traian Vuia no.6, Bucharest, Departement of Pharmaceutical Botany

Abstract:

The use of the species Clematis vitalba L. (Ranunculaceae) in the traditional medicine as an anti-inflamatory agent and the lack in chemical studies determined to start more detailed investigations. Carotenoides (in the leaf and in the flower), coumarins (in the stem), flavonosides, triterpenic saponins, polyphenolcarboxilic acids, tannins and polysaccharides (in the leaf, flower and stem) were identified. The phytobiological study revealed a cytotoxic effect (precipitated nuclear material, kinesis inhibition, rare nuclei with modified forms) for the leaf, and a chromatoclasic action (hypertrophied nuclei, anaphases with multiple bridges, telophases and anaphases in tropokinesis) for the flower.

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